Coenzyme Q10 (CoQ10)
There is some evidence that the supplement CoQ10 may help to reduce high blood pressure. A 12 week double-blind, placebo-controlled trial of 83 people with systolic hypertension examined the effect of CoQ10 supplements (60 mg twice daily). After the 12 weeks, there was a mean reduction in systolic blood pressure of 17.8 mm Hg in the Coq10-treated group.
Another study conducted at the University of Western Australia looked at the effect of CoQ10 on blood pressure and glycemic control in 74 people with type 2 diabetes. Participants were randomly assigned to receive either 100mg CoQ10 twice daily, 200mg of the drug fenfibrate, both, or neither for 12 weeks.
CoQ10 significantly reduced systolic and diastolic blood pressure(mean reduction 6.1 mm Hg and 2.9 mm Hg respectively). There was also a reduction in HbA1C, a marker for long-term glycemic control.
To learn more about CoQ10, read the Coenzyme Q10 (CoQ10) fact sheet.
In a meta-analysis of seven randomized controlled trials of garlic supplements, three trials showed a significant reduction in systolic blood pressure and four in diastolic blood pressure. Researchers concluded that garlic powder supplement may be of clinical use in patients with mild high blood pressure.
Garlic supplements should only be used under the supervision of a qualified health practitioner. Garlic can thin the blood (reduce the ability of blood to clot) similar to aspirin. Garlic may interact with many drugs and supplements such as the prescription drugs such as Coumadin (warfarin) or Trental (pentoxifylline), aspirin, vitamin E, gingko. It is usually recommended that people taking garlic stop in the weeks before and after any type of surgery.
To learn more about garlic, go to the articles about garlic
The herb hawthorn is often used by traditional herbal practitioners for high blood pressure.
In a randomized controlled trial conducted by researchers in Reading, UK, 79 patients with type 2 diabetes were randomized to receive either 1200 mg of hawthorn extract a day or placebo for 16 weeks. Medication for high blood pressure was used by 71 percent of the patients.
At the end of the 16 weeks, patients taking the hawthorn supplement had a significant reduction in mean diastolic blood pressure (2.6 mm Hg). No herb-drug interactions were reported.
Preliminary studies suggest that fish oil may have a modest effect on high blood pressure. Although fish oil supplements often contain both DHA (docohexaenoic acid) and EPA (eicosapentaenoic acid), there is some evidence that DHA is the ingredient that lowers high blood pressure. Learn more about fish oil.
Folate is a B vitamin necessary for formation of red blood cells. It may help to lower high blood pressure in some people, possibly by reducing elevated homocysteine levels.
One small study of 24 cigarette smokers found that four weeks of folic acid supplementation significantly lowered blood pressure. Learn more about folic acid.